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The potential of anti-malarial compounds derived from African medicinal plants. Part I: A pharmacological evaluation of alkaloids and terpenoids

Overview of attention for article published in Malaria Journal, December 2013
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  • Good Attention Score compared to outputs of the same age (75th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

Mentioned by

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7 tweeters
facebook
1 Facebook page

Citations

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111 Dimensions

Readers on

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137 Mendeley
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Title
The potential of anti-malarial compounds derived from African medicinal plants. Part I: A pharmacological evaluation of alkaloids and terpenoids
Published in
Malaria Journal, December 2013
DOI 10.1186/1475-2875-12-449
Pubmed ID
Authors

Pascal Amoa Onguéné, Fidele Ntie-Kang, Lydia Likowo Lifongo, Jean Claude Ndom, Wolfgang Sippl, Luc Meva’a Mbaze

Abstract

Traditional medicine caters for about 80% of the health care needs of many rural populations around the world, especially in developing countries. In addition, plant-derived compounds have played key roles in drug discovery. Malaria is currently a public health concern in many countries in the world due to factors such as chemotherapy faced by resistance, poor hygienic conditions, poorly managed vector control programmes and no approved vaccines. In this review, an attempt has been made to assess the value of African medicinal plants for drug discovery by discussing the anti-malarial virtue of the derived phytochemicals that have been tested by in vitro and in vivo assays. This survey was focused on pure compounds derived from African flora which have exhibited anti-malarial properties with activities ranging from "very active" to "weakly active". However, only the compounds which showed anti-malarial activities from "very active" to "moderately active" are discussed in this review. The activity of 278 compounds, mainly alkaloids, terpenoids, flavonoids, coumarines, phenolics, polyacetylenes, xanthones, quinones, steroids, and lignans have been discussed. The first part of this review series covers the activity of 171 compounds belonging to the alkaloid and terpenoid classes. Data available in the literature indicated that African flora hold an enormous potential for the development of phytomedicines for malaria.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
Burkina Faso 1 <1%
Ghana 1 <1%
Uganda 1 <1%
United States 1 <1%
Serbia 1 <1%
Unknown 130 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 16%
Student > Ph. D. Student 20 15%
Researcher 16 12%
Student > Bachelor 15 11%
Student > Postgraduate 9 7%
Other 24 18%
Unknown 31 23%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 21 15%
Chemistry 20 15%
Agricultural and Biological Sciences 16 12%
Medicine and Dentistry 13 9%
Biochemistry, Genetics and Molecular Biology 12 9%
Other 15 11%
Unknown 40 29%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2020.
All research outputs
#6,266,059
of 22,736,112 outputs
Outputs from Malaria Journal
#1,765
of 5,549 outputs
Outputs of similar age
#74,778
of 307,365 outputs
Outputs of similar age from Malaria Journal
#25
of 73 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 5,549 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,365 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.