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Resveratrol promotes myogenesis and hypertrophy in murine myoblasts

Overview of attention for article published in Journal of Translational Medicine, December 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

Mentioned by

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4 tweeters
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1 Facebook page

Citations

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66 Dimensions

Readers on

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95 Mendeley
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Title
Resveratrol promotes myogenesis and hypertrophy in murine myoblasts
Published in
Journal of Translational Medicine, December 2013
DOI 10.1186/1479-5876-11-310
Pubmed ID
Authors

Anna Montesano, Livio Luzi, Pamela Senesi, Nausicaa Mazzocchi, Ileana Terruzzi

Abstract

Nutrigenomics elucidate the ability of bioactive food components to influence gene expression, protein synthesis, degradation and post-translational modifications.Resveratrol (RSV), natural polyphenol found in grapes and in other fruits, has a plethora of health benefits in a variety of human diseases: cardio- and neuroprotection, immune regulation, cancer chemoprevention, DNA repair, prevention of mitochondrial disorder, avoidance of obesity-related diseases. In skeletal muscle, RSV acts on protein catabolism and muscle function, conferring resistance against oxidative stress, injury and cell death, but its action mechanisms and protein targets in myogenesis process are not completely known. Myogenesis is a dynamic multistep process regulated by Myogenic Regulator Factors (MRFs), responsible of the commitment of myogenic cell into skeletal muscle: mononucleated undifferentiated myoblasts break free from cell cycle, elongate and fuse to form multinucleated myotubes. Skeletal muscle hypertrophy can be defined as a result of an increase in the size of pre-existing skeletal muscle fibers accompanied by increased protein synthesis, mainly regulated by Insulin Like Growth Factor 1 (IGF-1), PI3-K/AKT signaling pathways.Aim of this work was the study of RSV effects on proliferation, differentiation process and hypertrophy in C2C12 murine cells.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
France 1 1%
Unknown 93 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 20%
Student > Bachelor 13 14%
Student > Master 12 13%
Researcher 11 12%
Student > Doctoral Student 6 6%
Other 13 14%
Unknown 21 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 21%
Biochemistry, Genetics and Molecular Biology 17 18%
Medicine and Dentistry 7 7%
Sports and Recreations 5 5%
Chemistry 4 4%
Other 13 14%
Unknown 29 31%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2020.
All research outputs
#10,190,210
of 18,038,980 outputs
Outputs from Journal of Translational Medicine
#1,287
of 3,300 outputs
Outputs of similar age
#129,446
of 276,639 outputs
Outputs of similar age from Journal of Translational Medicine
#104
of 246 outputs
Altmetric has tracked 18,038,980 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,300 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 276,639 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 246 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.