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Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes

Overview of attention for article published in Arthritis Research & Therapy, January 2013
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Citations

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Readers on

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67 Mendeley
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Title
Hypoxia promotes redifferentiation and suppresses markers of hypertrophy and degeneration in both healthy and osteoarthritic chondrocytes
Published in
Arthritis Research & Therapy, January 2013
DOI 10.1186/ar4272
Pubmed ID
Authors

Brandon D Markway, Holly Cho, Brian Johnstone

Abstract

Hypoxia is considered to be a positive influence on the healthy chondrocyte phenotype and cartilage matrix formation. However, hypoxia-inducible factors (HIFs) have been implicated in the pathogenesis of osteoarthritis (OA). Thus, we assessed whether healthy and OA chondrocytes have distinct responses to oxygen, particularly with regard to hypertrophy and degradation during redifferentiation.

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Italy 1 1%
Unknown 65 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 30%
Researcher 12 18%
Student > Master 8 12%
Student > Bachelor 5 7%
Other 5 7%
Other 10 15%
Unknown 7 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 25%
Biochemistry, Genetics and Molecular Biology 12 18%
Medicine and Dentistry 11 16%
Engineering 8 12%
Physics and Astronomy 2 3%
Other 5 7%
Unknown 12 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 December 2013.
All research outputs
#2,017,177
of 3,628,496 outputs
Outputs from Arthritis Research & Therapy
#432
of 811 outputs
Outputs of similar age
#52,799
of 104,461 outputs
Outputs of similar age from Arthritis Research & Therapy
#30
of 53 outputs
Altmetric has tracked 3,628,496 research outputs across all sources so far. This one is in the 25th percentile – i.e., 25% of other outputs scored the same or lower than it.
So far Altmetric has tracked 811 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,461 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.