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Chronic hepatitis infection is associated with extrahepatic cancer development: a nationwide population-based study in Taiwan

Overview of attention for article published in BMC Cancer, November 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

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2 news outlets
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94 Dimensions

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52 Mendeley
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Title
Chronic hepatitis infection is associated with extrahepatic cancer development: a nationwide population-based study in Taiwan
Published in
BMC Cancer, November 2016
DOI 10.1186/s12885-016-2918-5
Pubmed ID
Authors

Abram Bunya Kamiza, Fu-Hsiung Su, Wen-Chang Wang, Fung-Chang Sung, Shih-Ni Chang, Chih-Ching Yeh

Abstract

Hepatitis B virus (HBV) and hepatitis C virus (HCV) are the major causes of chronic hepatitis infection (CHI). This longitudinal cohort study investigated the association of CHI with hepatic and extrahepatic cancer development in Taiwan. Patients with HBV infection and HCV infection were identified from the Taiwan National Health Insurance Research Database. A Cox proportional hazard model was used to calculate hazard ratios (HRs) and 95 % confidence intervals (CIs) for determining the association between CHI and cancer development. The patients with HBV infection exhibited an increased risk of colorectal cancer (HR: 1.36, 95 % CI: 1.09-1.70), liver cancer (HR: 21.47, 95 % CI: 18.0-25.6), gallbladder and extrahepatic bile duct cancer (HR: 2.05, 95 % CI: 1.07-3.91), pancreatic cancer (HR: 2.61, 95 % CI: 1.47-4.61), kidney cancer (HR: 1.72, 95 % CI: 1.10-2.68), ovarian cancer (HR: 2.31, 95 % CI: 1.21-4.39), and non-Hodgkin's lymphoma (HR: 2.10, 95 % CI: 1.25-3.52). The patients with HCV infection exhibited an increased risk of liver cancer (HR: 25.10, 95 % CI: 20.9-30.2), gallbladder and extrahepatic bile duct cancer (HR: 2.60, 95 % CI: 1.42-4.73), ovarian cancer (HR: 5.15, 95 % CI: 1.98-13.4), and non-Hodgkin's lymphoma (HR: 2.30, 95 % CI: 1.34-3.96). The present population-based study revealed that in addition to its association with primary liver cancer, CHI is associated with an increased risk of extrahepatic cancer.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 12%
Student > Master 6 12%
Student > Ph. D. Student 5 10%
Student > Bachelor 4 8%
Student > Doctoral Student 3 6%
Other 10 19%
Unknown 18 35%
Readers by discipline Count As %
Medicine and Dentistry 20 38%
Biochemistry, Genetics and Molecular Biology 6 12%
Nursing and Health Professions 2 4%
Economics, Econometrics and Finance 1 2%
Immunology and Microbiology 1 2%
Other 2 4%
Unknown 20 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 July 2019.
All research outputs
#1,857,530
of 22,968,808 outputs
Outputs from BMC Cancer
#291
of 8,345 outputs
Outputs of similar age
#35,215
of 313,424 outputs
Outputs of similar age from BMC Cancer
#6
of 111 outputs
Altmetric has tracked 22,968,808 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,345 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,424 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 111 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.