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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Changes of peripheral TGF-β1 depend on monocytes-derived macrophages in Huntington disease
|
|---|---|
| Published in |
Molecular Brain, December 2013
|
| DOI | 10.1186/1756-6606-6-55 |
| Pubmed ID | |
| Authors |
Alba Di Pardo, Silvia Alberti, Vittorio Maglione, Enrico Amico, Etty P Cortes, Francesca Elifani, Giuseppe Battaglia, Carla L Busceti, Ferdinando Nicoletti, JeanPaul G Vonsattel, Ferdinando Squitieri |
| Abstract |
Huntington Disease (HD) is a neurodegenerative disorder resulting from the expansion of polyglutamine stretch in the huntingtin protein (Htt). Mutant HTT (mHtt) leads to progressive impairment of several molecular pathways that have been linked to disease pathogenesis. Defects in the production of a number of neurotrophic factors have been described as important determinants contributing to the development of HD. We have previously demonstrated that production of transforming growth factor-β1 (TGF-β1) is also deregulated in HD. Peripheral levels of TGF-β1 were markedly reduced early in the disease and returned to normal levels with disease severity. However, the cause and the biochemical origin of such abnormalities are still unclear. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Italy | 1 | 2% |
| Unknown | 47 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 27% |
| Student > Ph. D. Student | 9 | 18% |
| Student > Master | 5 | 10% |
| Student > Bachelor | 3 | 6% |
| Student > Doctoral Student | 3 | 6% |
| Other | 5 | 10% |
| Unknown | 11 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 7 | 14% |
| Biochemistry, Genetics and Molecular Biology | 6 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 10% |
| Agricultural and Biological Sciences | 5 | 10% |
| Medicine and Dentistry | 5 | 10% |
| Other | 8 | 16% |
| Unknown | 13 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2014.
All research outputs
#14,768,891
of 22,738,543 outputs
Outputs from Molecular Brain
#624
of 1,103 outputs
Outputs of similar age
#185,701
of 307,365 outputs
Outputs of similar age from Molecular Brain
#14
of 31 outputs
Altmetric has tracked 22,738,543 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,103 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,365 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.