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Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo

Overview of attention for article published in BMC Cancer, December 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
2 tweeters
patent
1 patent

Citations

dimensions_citation
57 Dimensions

Readers on

mendeley
58 Mendeley
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Title
Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo
Published in
BMC Cancer, December 2013
DOI 10.1186/1471-2407-13-604
Pubmed ID
Authors

Ryan Montano, Ruth Thompson, Injae Chung, Huagang Hou, Nadeem Khan, Alan Eastman

Abstract

Chk1 inhibitors have emerged as promising anticancer therapeutic agents particularly when combined with antimetabolites such as gemcitabine, cytarabine or hydroxyurea. Here, we address the importance of appropriate drug scheduling when gemcitabine is combined with the Chk1 inhibitor MK-8776, and the mechanisms involved in the schedule dependence.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 2%
Unknown 57 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 22%
Researcher 12 21%
Student > Bachelor 6 10%
Student > Master 5 9%
Student > Postgraduate 4 7%
Other 13 22%
Unknown 5 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 29%
Medicine and Dentistry 14 24%
Agricultural and Biological Sciences 13 22%
Chemistry 3 5%
Engineering 2 3%
Other 4 7%
Unknown 5 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2017.
All research outputs
#4,868,021
of 17,367,552 outputs
Outputs from BMC Cancer
#1,190
of 6,315 outputs
Outputs of similar age
#70,504
of 272,585 outputs
Outputs of similar age from BMC Cancer
#65
of 360 outputs
Altmetric has tracked 17,367,552 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 6,315 research outputs from this source. They receive a mean Attention Score of 4.1. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 272,585 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 360 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.