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Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo

Overview of attention for article published in BMC Cancer, December 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

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2 X users
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2 patents

Citations

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69 Dimensions

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70 Mendeley
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Title
Sensitization of human cancer cells to gemcitabine by the Chk1 inhibitor MK-8776: cell cycle perturbation and impact of administration schedule in vitro and in vivo
Published in
BMC Cancer, December 2013
DOI 10.1186/1471-2407-13-604
Pubmed ID
Authors

Ryan Montano, Ruth Thompson, Injae Chung, Huagang Hou, Nadeem Khan, Alan Eastman

Abstract

Chk1 inhibitors have emerged as promising anticancer therapeutic agents particularly when combined with antimetabolites such as gemcitabine, cytarabine or hydroxyurea. Here, we address the importance of appropriate drug scheduling when gemcitabine is combined with the Chk1 inhibitor MK-8776, and the mechanisms involved in the schedule dependence.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 1%
Unknown 69 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 20%
Student > Ph. D. Student 13 19%
Student > Bachelor 8 11%
Student > Master 6 9%
Student > Doctoral Student 4 6%
Other 13 19%
Unknown 12 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 19 27%
Medicine and Dentistry 14 20%
Agricultural and Biological Sciences 14 20%
Chemistry 5 7%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 4 6%
Unknown 11 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 November 2021.
All research outputs
#6,399,505
of 22,736,112 outputs
Outputs from BMC Cancer
#1,630
of 8,272 outputs
Outputs of similar age
#76,396
of 306,115 outputs
Outputs of similar age from BMC Cancer
#19
of 103 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 8,272 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,115 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.