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Anti-inflammatory effects of fish oil in ovaries of laying hens target prostaglandin pathways

Overview of attention for article published in Lipids in Health and Disease, October 2013
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Title
Anti-inflammatory effects of fish oil in ovaries of laying hens target prostaglandin pathways
Published in
Lipids in Health and Disease, October 2013
DOI 10.1186/1476-511x-12-152
Pubmed ID
Authors

Erfan Eilati, Carolynn C Small, Stacey R McGee, Nawneet K Kurrey, Dale Buchanan Hales

Abstract

An effective way to control cancer is by prevention. Ovarian cancer is the most lethal gynecological malignancy. Progress in the treatment and prevention of ovarian cancer has been hampered due to the lack of an appropriate animal model and absence of effective chemo-prevention strategies. The domestic hens spontaneously develop ovarian adenocarcinomas that share similar histological appearance and symptoms such as ascites and metastasis with humans. There is a link between chronic inflammation and cancer. Prostaglandin E2 (PGE2) is the most pro-inflammatory ecoisanoid and one of the downstream products of two isoforms of cyclooxygenase (COX) enzymes: COX-1 and COX-2. PGE2 exerts its effects on target cells by coupling to four subtypes of receptors which have been classified as EP1-4. Fish oil is a source of omega-3 fatty acids (OM-3FAs) which may be effective in prevention of ovarian cancer. Our objective was to assess the potential impact of fish oil on expression of COX enzymes, PGE2 concentration, apoptosis and proliferation in ovaries of laying hens.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 4%
Unknown 27 96%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 14%
Student > Master 4 14%
Student > Ph. D. Student 4 14%
Other 2 7%
Student > Doctoral Student 2 7%
Other 4 14%
Unknown 8 29%
Readers by discipline Count As %
Medicine and Dentistry 8 29%
Agricultural and Biological Sciences 6 21%
Biochemistry, Genetics and Molecular Biology 3 11%
Veterinary Science and Veterinary Medicine 1 4%
Neuroscience 1 4%
Other 1 4%
Unknown 8 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2014.
All research outputs
#17,708,224
of 22,738,543 outputs
Outputs from Lipids in Health and Disease
#921
of 1,440 outputs
Outputs of similar age
#151,518
of 212,023 outputs
Outputs of similar age from Lipids in Health and Disease
#17
of 24 outputs
Altmetric has tracked 22,738,543 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,440 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,023 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 29th percentile – i.e., 29% of its contemporaries scored the same or lower than it.