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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Distinct DNA methylation patterns of cognitive impairment and trisomy 21 in down syndrome
|
|---|---|
| Published in |
BMC Medical Genomics, December 2013
|
| DOI | 10.1186/1755-8794-6-58 |
| Pubmed ID | |
| Authors |
Meaghan J Jones, Pau Farré, Lisa M McEwen, Julia L MacIsaac, Kim Watt, Sarah M Neumann, Eldon Emberly, Max S Cynader, Naznin Virji-Babul, Michael S Kobor |
| Abstract |
The presence of an extra whole or part of chromosome 21 in people with Down syndrome (DS) is associated with multiple neurological changes, including pathological aging that often meets the criteria for Alzheimer's Disease (AD). In addition, trisomies have been shown to disrupt normal epigenetic marks across the genome, perhaps in response to changes in gene dosage. We hypothesized that trisomy 21 would result in global epigenetic changes across all participants, and that DS patients with cognitive impairment would show an additional epigenetic signature. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
| Members of the public | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 1 | 1% |
| Unknown | 92 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 19% |
| Student > Bachelor | 18 | 19% |
| Student > Master | 13 | 14% |
| Researcher | 13 | 14% |
| Student > Doctoral Student | 5 | 5% |
| Other | 15 | 16% |
| Unknown | 11 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 29 | 31% |
| Biochemistry, Genetics and Molecular Biology | 14 | 15% |
| Medicine and Dentistry | 13 | 14% |
| Neuroscience | 11 | 12% |
| Nursing and Health Professions | 5 | 5% |
| Other | 9 | 10% |
| Unknown | 12 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 January 2014.
All research outputs
#13,300,167
of 22,738,543 outputs
Outputs from BMC Medical Genomics
#492
of 1,218 outputs
Outputs of similar age
#163,072
of 306,082 outputs
Outputs of similar age from BMC Medical Genomics
#7
of 12 outputs
Altmetric has tracked 22,738,543 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,218 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,082 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.