Title |
ANCA-associated vasculitis in childhood: recent advances
|
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Published in |
Italian Journal of Pediatrics, May 2017
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DOI | 10.1186/s13052-017-0364-x |
Pubmed ID | |
Authors |
Marta Calatroni, Elena Oliva, Davide Gianfreda, Gina Gregorini, Marco Allinovi, Giuseppe A. Ramirez, Enrica P. Bozzolo, Sara Monti, Claudia Bracaglia, Giulia Marucci, Monica Bodria, Renato A. Sinico, Federico Pieruzzi, Gabriella Moroni, Serena Pastore, Giacomo Emmi, Pasquale Esposito, Mariagrazia Catanoso, Giancarlo Barbano, Alice Bonanni, Augusto Vaglio |
Abstract |
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are rare systemic diseases that usually occur in adulthood. They comprise granulomatosis with polyangiitis (GPA, Wegener's), microscopic polyangiitis (MPA) and eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss syndrome). Their clinical presentation is often heterogeneous, with frequent involvement of the respiratory tract, the kidney, the skin and the joints. ANCA-associated vasculitis is rare in childhood but North-American and European cohort studies performed during the last decade have clarified their phenotype, patterns of renal involvement and their prognostic implications, and outcome. Herein, we review the main clinical and therapeutic aspects of childhood-onset ANCA-associated vasculitis, and provide preliminary data on demographic characteristics and organ manifestations of an Italian multicentre cohort. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Ecuador | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 94 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 14 | 15% |
Student > Bachelor | 10 | 11% |
Researcher | 9 | 10% |
Student > Postgraduate | 9 | 10% |
Student > Doctoral Student | 6 | 6% |
Other | 18 | 19% |
Unknown | 28 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 54 | 57% |
Biochemistry, Genetics and Molecular Biology | 3 | 3% |
Nursing and Health Professions | 2 | 2% |
Agricultural and Biological Sciences | 2 | 2% |
Immunology and Microbiology | 1 | 1% |
Other | 3 | 3% |
Unknown | 29 | 31% |