↓ Skip to main content

Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition

Overview of attention for article published in BMC Cancer, January 2014
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

twitter
5 X users
facebook
1 Facebook page

Citations

dimensions_citation
391 Dimensions

Readers on

mendeley
156 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition
Published in
BMC Cancer, January 2014
DOI 10.1186/1471-2407-14-1
Pubmed ID
Authors

Gaofeng Xiong, Lei Deng, Jieqing Zhu, Piotr G Rychahou, Ren Xu

Abstract

Increased collagen deposition provides physical and biochemical signals to support tumor growth and invasion during breast cancer development. Therefore, inhibition of collagen synthesis and deposition has been considered a strategy to suppress breast cancer progression. Collagen prolyl-4-hydroxylase α subunit 2 (P4HA2), an enzyme hydroxylating proline residues in -X-Pro-Gly- sequences, is a potential therapeutic target for the disorders associated with increased collagen deposition. However, expression and function of P4HA2 in breast cancer progression are not well investigated.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 156 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Spain 1 <1%
Denmark 1 <1%
Germany 1 <1%
Unknown 151 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 22%
Researcher 20 13%
Student > Bachelor 19 12%
Student > Master 17 11%
Student > Doctoral Student 8 5%
Other 19 12%
Unknown 39 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 44 28%
Medicine and Dentistry 27 17%
Agricultural and Biological Sciences 23 15%
Pharmacology, Toxicology and Pharmaceutical Science 4 3%
Neuroscience 3 2%
Other 17 11%
Unknown 38 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 March 2015.
All research outputs
#13,167,140
of 22,738,543 outputs
Outputs from BMC Cancer
#2,827
of 8,272 outputs
Outputs of similar age
#160,386
of 305,194 outputs
Outputs of similar age from BMC Cancer
#34
of 101 outputs
Altmetric has tracked 22,738,543 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,272 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,194 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.