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Mesenchymal stem cell therapy in type 2 diabetes mellitus

Overview of attention for article published in Diabetology & Metabolic Syndrome, May 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

twitter
3 tweeters
patent
1 patent
facebook
1 Facebook page
f1000
1 research highlight platform

Citations

dimensions_citation
54 Dimensions

Readers on

mendeley
132 Mendeley
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Title
Mesenchymal stem cell therapy in type 2 diabetes mellitus
Published in
Diabetology & Metabolic Syndrome, May 2017
DOI 10.1186/s13098-017-0233-1
Pubmed ID
Authors

Li Zang, Haojie Hao, Jiejie Liu, Yijun Li, Weidong Han, Yiming Mu

Abstract

Type 2 diabetes mellitus (T2DM), which is characterized by the combination of relative insulin deficiency and insulin resistance, cannot be reversed with existing therapeutic strategies. Transplantation of insulin-producing cells (IPCs) was once thought to be the most promising strategy for treating diabetes, but the pace from the laboratory to clinical application has been obstructed due to its drawbacks. Mesenchymal stem cells (MSCs) harbor differentiation potential, immunosuppressive properties, and anti-inflammatory effects, and they are considered an ideal candidate cell type for treatment of DM. MSC-related research has demonstrated exciting therapeutic effects in glycemic control both in vivo and in vitro, and these results now have been translated into clinical practice. However, some critical potential problems have emerged from current clinical trials. Multi-center, large-scale, double-blind, and placebo-controlled studies with strict supervision are required before MSC transplantation can become a routine therapeutic approach for T2DM. We briefly review the molecular mechanism of MSC treatment for T2DM as well as the merits and drawbacks identified in current clinical trials.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 132 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 26 20%
Student > Master 17 13%
Student > Ph. D. Student 15 11%
Researcher 9 7%
Student > Doctoral Student 7 5%
Other 16 12%
Unknown 42 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 30 23%
Medicine and Dentistry 25 19%
Agricultural and Biological Sciences 11 8%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Nursing and Health Professions 3 2%
Other 14 11%
Unknown 44 33%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 May 2020.
All research outputs
#3,427,079
of 17,719,454 outputs
Outputs from Diabetology & Metabolic Syndrome
#89
of 489 outputs
Outputs of similar age
#69,607
of 274,812 outputs
Outputs of similar age from Diabetology & Metabolic Syndrome
#2
of 5 outputs
Altmetric has tracked 17,719,454 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 489 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,812 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.