Title |
Replication of an empirical approach to delineate the heterogeneity of chronic unexplained fatigue
|
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Published in |
Population Health Metrics, October 2009
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DOI | 10.1186/1478-7954-7-17 |
Pubmed ID | |
Authors |
Eric Aslakson, Uté Vollmer-Conna, William C Reeves, Peter D White |
Abstract |
Chronic fatigue syndrome (CFS) is defined by self-reported symptoms. There are no diagnostic signs or laboratory markers, and the pathophysiology remains inchoate. In part, difficulties identifying and replicating biomarkers and elucidating the pathophysiology reflect the heterogeneous nature of the syndromic illness CFS. We conducted this analysis of people from defined metropolitan, urban, and rural populations to replicate our earlier empirical delineation of medically unexplained chronic fatigue and CFS into discrete endophenotypes. Both the earlier and current analyses utilized quantitative measures of functional impairment and symptoms as well as laboratory data. This study and the earlier one enrolled participants from defined populations and measured the internal milieu, which differentiates them from studies of clinic referrals that examine only clinical phenotypes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Greece | 1 | 2% |
Unknown | 47 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 13 | 27% |
Student > Ph. D. Student | 7 | 15% |
Researcher | 6 | 13% |
Student > Master | 5 | 10% |
Student > Postgraduate | 4 | 8% |
Other | 9 | 19% |
Unknown | 4 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 16 | 33% |
Medicine and Dentistry | 14 | 29% |
Agricultural and Biological Sciences | 3 | 6% |
Computer Science | 2 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Other | 3 | 6% |
Unknown | 9 | 19% |