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HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV

Overview of attention for article published in Retrovirology, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

blogs
1 blog
twitter
8 X users
wikipedia
1 Wikipedia page
googleplus
1 Google+ user
video
1 YouTube creator

Citations

dimensions_citation
31 Dimensions

Readers on

mendeley
67 Mendeley
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Title
HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV
Published in
Retrovirology, January 2014
DOI 10.1186/1742-4690-11-2
Pubmed ID
Authors

Marta García-Montojo, Belén de la Hera, Jezabel Varadé, Ana de la Encarnación, Iris Camacho, María Domínguez-Mozo, Ana Arias-Leal, Ángel García-Martínez, Ignacio Casanova, Guillermo Izquierdo, Miguel Lucas, Maria Fedetz, Antonio Alcina, Rafael Arroyo, Fuencisla Matesanz, Elena Urcelay, Roberto Alvarez-Lafuente

Abstract

Multiple Sclerosis (MS) is an autoimmune demyelinating disease that occurs more frequently in women than in men. Multiple Sclerosis Associated Retrovirus (MSRV) is a member of HERV-W, a multicopy human endogenous retroviral family repeatedly implicated in MS pathogenesis. MSRV envelope protein is elevated in the serum of MS patients and induces inflammation and demyelination but, in spite of this pathogenic potential, its exact genomic origin and mechanism of generation are unknown. A possible link between the HERV-W copy on chromosome Xq22.3, that contains an almost complete open reading frame, and the gender differential prevalence in MS has been suggested.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Iran, Islamic Republic of 1 1%
Spain 1 1%
United States 1 1%
Canada 1 1%
Unknown 63 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 18%
Student > Ph. D. Student 10 15%
Student > Bachelor 7 10%
Other 6 9%
Student > Doctoral Student 5 7%
Other 18 27%
Unknown 9 13%
Readers by discipline Count As %
Medicine and Dentistry 15 22%
Agricultural and Biological Sciences 15 22%
Biochemistry, Genetics and Molecular Biology 8 12%
Neuroscience 8 12%
Immunology and Microbiology 4 6%
Other 8 12%
Unknown 9 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2023.
All research outputs
#2,039,311
of 24,493,053 outputs
Outputs from Retrovirology
#81
of 1,136 outputs
Outputs of similar age
#23,463
of 315,601 outputs
Outputs of similar age from Retrovirology
#2
of 40 outputs
Altmetric has tracked 24,493,053 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,136 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,601 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.