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Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies

Overview of attention for article published in Journal of Neuroinflammation, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

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4 X users
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1 patent

Citations

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85 Mendeley
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Title
Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies
Published in
Journal of Neuroinflammation, January 2014
DOI 10.1186/1742-2094-11-6
Pubmed ID
Authors

Irene Paterniti, Daniela Impellizzeri, Rosanna Di Paola, Emanuela Esposito, Stacy Gladman, Ping Yip, John V Priestley, Adina T Michael-Titus, Salvatore Cuzzocrea

Abstract

Two families of polyunsaturated fatty acid (PUFA), omega-3 (ω-3) and omega-6 (ω-6), are required for physiological functions. The long chain ω-3 PUFAs, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have significant biological effects. In particular, DHA is a major component of cell membranes in the brain. It is also involved in neurotransmission. Spinal cord injury (SCI) is a highly devastating pathology that can lead to catastrophic dysfunction, with a significant reduction in the quality of life. Previous studies have shown that EPA and DHA can exert neuroprotective effects in SCI in mice and rats. The aim of this study was to analyze the mechanism of action of ω-3 PUFAs, such as DHA, in a mouse model of SCI, with a focus on the early pathophysiological processes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Romania 1 1%
Unknown 83 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 17 20%
Student > Ph. D. Student 14 16%
Researcher 13 15%
Student > Doctoral Student 6 7%
Student > Bachelor 6 7%
Other 15 18%
Unknown 14 16%
Readers by discipline Count As %
Medicine and Dentistry 16 19%
Agricultural and Biological Sciences 14 16%
Neuroscience 13 15%
Biochemistry, Genetics and Molecular Biology 10 12%
Pharmacology, Toxicology and Pharmaceutical Science 4 5%
Other 11 13%
Unknown 17 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2017.
All research outputs
#5,586,415
of 22,739,983 outputs
Outputs from Journal of Neuroinflammation
#999
of 2,617 outputs
Outputs of similar age
#64,583
of 304,956 outputs
Outputs of similar age from Journal of Neuroinflammation
#18
of 59 outputs
Altmetric has tracked 22,739,983 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,617 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,956 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.