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Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis

Overview of attention for article published in Critical Care, June 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

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2 X users
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9 patents

Citations

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136 Dimensions

Readers on

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203 Mendeley
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Title
Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis
Published in
Critical Care, June 2011
DOI 10.1186/cc10274
Pubmed ID
Authors

Allison Sutherland, Mervyn Thomas, Roslyn A Brandon, Richard B Brandon, Jeffrey Lipman, Benjamin Tang, Anthony McLean, Ranald Pascoe, Gareth Price, Thu Nguyen, Glenn Stone, Deon Venter

Abstract

Sepsis is a complex immunological response to infection characterized by early hyper-inflammation followed by severe and protracted immunosuppression, suggesting that a multi-marker approach has the greatest clinical utility for early detection, within a clinical environment focused on Systemic Inflammatory Response Syndrome (SIRS) differentiation. Pre-clinical research using an equine sepsis model identified a panel of gene expression biomarkers that define the early aberrant immune activation. Thus, the primary objective was to apply these gene expression biomarkers to distinguish patients with sepsis from those who had undergone major open surgery and had clinical outcomes consistent with systemic inflammation due to physical trauma and wound healing.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 203 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 2 <1%
Norway 1 <1%
Australia 1 <1%
Brazil 1 <1%
United Kingdom 1 <1%
Canada 1 <1%
United States 1 <1%
Unknown 195 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 39 19%
Student > Ph. D. Student 31 15%
Student > Master 24 12%
Other 14 7%
Professor 13 6%
Other 40 20%
Unknown 42 21%
Readers by discipline Count As %
Medicine and Dentistry 71 35%
Agricultural and Biological Sciences 32 16%
Biochemistry, Genetics and Molecular Biology 10 5%
Computer Science 7 3%
Immunology and Microbiology 7 3%
Other 26 13%
Unknown 50 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 June 2021.
All research outputs
#3,202,152
of 25,373,627 outputs
Outputs from Critical Care
#2,616
of 6,554 outputs
Outputs of similar age
#15,753
of 126,622 outputs
Outputs of similar age from Critical Care
#11
of 50 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 126,622 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.