Title |
Inhibitors compounds of the flavivirus replication process
|
---|---|
Published in |
Virology Journal, May 2017
|
DOI | 10.1186/s12985-017-0761-1 |
Pubmed ID | |
Authors |
Leidy L. García, Leonardo Padilla, Jhon C. Castaño |
Abstract |
Flaviviruses are small viruses with single-stranded RNA, which include the yellow fever virus, dengue virus, West Nile virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus; and are causal agents of the most important emerging diseases that have no available treatment to date. In recent years, the strategy has focused on the development of replication inhibitors of these viruses designed to act mainly by affecting the activity of enzyme proteins, such as NS3 and NS5, which perform important functions in the viral replication process. This article describes the importance of flaviviruses and the development of molecules used as inhibitors of viral replication in this genus. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 4 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 2 | 50% |
Members of the public | 1 | 25% |
Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | <1% |
Unknown | 208 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 38 | 18% |
Student > Bachelor | 36 | 17% |
Student > Ph. D. Student | 30 | 14% |
Researcher | 18 | 9% |
Student > Doctoral Student | 17 | 8% |
Other | 32 | 15% |
Unknown | 38 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 44 | 21% |
Agricultural and Biological Sciences | 28 | 13% |
Chemistry | 28 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 14 | 7% |
Immunology and Microbiology | 12 | 6% |
Other | 31 | 15% |
Unknown | 52 | 25% |