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Effect of TTP488 in patients with mild to moderate Alzheimer’s disease

Overview of attention for article published in BMC Neurology, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

blogs
2 blogs
twitter
4 X users

Citations

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100 Dimensions

Readers on

mendeley
109 Mendeley
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Title
Effect of TTP488 in patients with mild to moderate Alzheimer’s disease
Published in
BMC Neurology, January 2014
DOI 10.1186/1471-2377-14-12
Pubmed ID
Authors

Aaron H Burstein, Imogene Grimes, Douglas R Galasko, Paul S Aisen, Marwan Sabbagh, Adnan MM Mjalli

Abstract

TTP488, an antagonist at the Receptor for Advanced Glycation End products, was evaluated as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD). A previous report describes decreased decline in ADAS-cog (delta = 3.1, p = 0.008 at 18 months, ANCOVA with multiple imputation), relative to placebo, following a 5 mg/day dose of TTP488. Acute, reversible cognitive worsening was seen with a 20 mg/day dose. The present study further evaluates the efficacy of TTP488 by subgroup analyses based on disease severity and concentration effect analysis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Japan 1 <1%
United States 1 <1%
South Africa 1 <1%
Unknown 104 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 17%
Student > Master 16 15%
Student > Ph. D. Student 12 11%
Other 12 11%
Student > Bachelor 10 9%
Other 15 14%
Unknown 25 23%
Readers by discipline Count As %
Medicine and Dentistry 25 23%
Biochemistry, Genetics and Molecular Biology 12 11%
Pharmacology, Toxicology and Pharmaceutical Science 11 10%
Agricultural and Biological Sciences 10 9%
Neuroscience 7 6%
Other 12 11%
Unknown 32 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2019.
All research outputs
#1,849,428
of 23,801,276 outputs
Outputs from BMC Neurology
#157
of 2,526 outputs
Outputs of similar age
#23,906
of 334,726 outputs
Outputs of similar age from BMC Neurology
#5
of 62 outputs
Altmetric has tracked 23,801,276 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,526 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,726 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.