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Citrate confers less filter-induced complement activation and neutrophil degranulation than heparin when used for anticoagulation during continuous venovenous haemofiltration in critically ill…

Overview of attention for article published in BMC Nephrology, January 2014
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Title
Citrate confers less filter-induced complement activation and neutrophil degranulation than heparin when used for anticoagulation during continuous venovenous haemofiltration in critically ill patients
Published in
BMC Nephrology, January 2014
DOI 10.1186/1471-2369-15-19
Pubmed ID
Authors

Louise Schilder, S Azam Nurmohamed, Pieter M ter Wee, Nanne J Paauw, Armand RJ Girbes, Albertus Beishuizen, Robert HJ Beelen, AB Johan Groeneveld

Abstract

During continuous venovenous haemofiltration (CVVH), regional anticoagulation with citrate may be superior to heparin in terms of biocompatibility, since heparin as opposed to citrate may activate complement (reflected by circulating C5a) and induce neutrophil degranulation in the filter and myeloperoxidase (MPO) release from endothelium.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 18%
Other 5 13%
Student > Postgraduate 5 13%
Student > Master 5 13%
Professor > Associate Professor 3 8%
Other 9 23%
Unknown 5 13%
Readers by discipline Count As %
Medicine and Dentistry 19 49%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Nursing and Health Professions 3 8%
Chemical Engineering 1 3%
Business, Management and Accounting 1 3%
Other 6 15%
Unknown 6 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2014.
All research outputs
#17,709,056
of 22,739,983 outputs
Outputs from BMC Nephrology
#1,698
of 2,461 outputs
Outputs of similar age
#219,158
of 304,587 outputs
Outputs of similar age from BMC Nephrology
#30
of 56 outputs
Altmetric has tracked 22,739,983 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,461 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,587 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.