Title |
Natural antisense RNAs as mRNA regulatory elements in bacteria: a review on function and applications
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Published in |
Cellular & Molecular Biology Letters, July 2016
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DOI | 10.1186/s11658-016-0007-z |
Pubmed ID | |
Authors |
Fatemeh Saberi, Mehdi Kamali, Ali Najafi, Alavieh Yazdanparast, Mehrdad Moosazadeh Moghaddam |
Abstract |
Naturally occurring antisense RNAs are small, diffusible, untranslated transcripts that pair to target RNAs at specific regions of complementarity to control their biological function by regulating gene expression at the post-transcriptional level. This review focuses on known cases of antisense RNA control in prokaryotes and provides an overview of some natural RNA-based mechanisms that bacteria use to modulate gene expression, such as mRNA sensors, riboswitches and antisense RNAs. We also highlight recent advances in RNA-based technology. The review shows that studies on both natural and synthetic systems are reciprocally beneficial. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
China | 1 | <1% |
Unknown | 196 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 42 | 21% |
Student > Bachelor | 29 | 15% |
Student > Master | 25 | 13% |
Researcher | 24 | 12% |
Student > Doctoral Student | 10 | 5% |
Other | 23 | 12% |
Unknown | 45 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 74 | 37% |
Agricultural and Biological Sciences | 34 | 17% |
Immunology and Microbiology | 11 | 6% |
Engineering | 5 | 3% |
Medicine and Dentistry | 5 | 3% |
Other | 21 | 11% |
Unknown | 48 | 24% |