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The identification of human aldo-keto reductase AKR7A2 as a novel cytoglobin-binding partner

Overview of attention for article published in Cellular & Molecular Biology Letters, October 2016
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Title
The identification of human aldo-keto reductase AKR7A2 as a novel cytoglobin-binding partner
Published in
Cellular & Molecular Biology Letters, October 2016
DOI 10.1186/s11658-016-0026-9
Pubmed ID
Authors

Xin Li, Shanshan Zou, Zhen Li, Gaotai Cai, Bohong Chen, Ping Wang, Wenqi Dong

Abstract

Cytoglobin (CYGB), a member of the globin family, is thought to protect cells from reactive oxygen and nitrogen species and deal with hypoxic conditions and oxidative stress. However, its molecular mechanisms of action are not clearly understood. Through immunoprecipitation combined with a two-dimensional electrophoresis-mass spectrometry assay, we identified a CYGB interactor: aldo-keto reductase family 7 member A2 (AKR7A2). The interaction was further confirmed using yeast two-hybrid and co-immunoprecipitation assays. Our results show that AKR7A2 physically interacts with CYGB.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 40%
Researcher 3 30%
Student > Bachelor 1 10%
Student > Doctoral Student 1 10%
Unknown 1 10%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 40%
Pharmacology, Toxicology and Pharmaceutical Science 1 10%
Agricultural and Biological Sciences 1 10%
Chemistry 1 10%
Engineering 1 10%
Other 0 0%
Unknown 2 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2017.
All research outputs
#20,425,762
of 22,977,819 outputs
Outputs from Cellular & Molecular Biology Letters
#414
of 482 outputs
Outputs of similar age
#271,864
of 314,377 outputs
Outputs of similar age from Cellular & Molecular Biology Letters
#7
of 8 outputs
Altmetric has tracked 22,977,819 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 482 research outputs from this source. They receive a mean Attention Score of 2.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,377 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
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