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X Demographics
Mendeley readers
Attention Score in Context
| Title |
GraphProt: modeling binding preferences of RNA-binding proteins
|
|---|---|
| Published in |
Genome Biology, January 2014
|
| DOI | 10.1186/gb-2014-15-1-r17 |
| Pubmed ID | |
| Authors |
Daniel Maticzka, Sita J Lange, Fabrizio Costa, Rolf Backofen |
| Abstract |
We present GraphProt, a computational framework for learning sequence- and structure-binding preferences of RNA-binding proteins (RBPs) from high-throughput experimental data. We benchmark GraphProt, demonstrating that the modeled binding preferences conform to the literature, and showcase the biological relevance and two applications of GraphProt models. First, estimated binding affinities correlate with experimental measurements. Second, predicted Ago2 targets display higher levels of expression upon Ago2 knockdown, whereas control targets do not. Computational binding models, such as those provided by GraphProt, are essential to predict RBP-binding sites and affinities in all tissues. GraphProt is freely available at http://www.bioinf.uni-freiburg.de/Software/GraphProt. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 20% |
| United States | 2 | 20% |
| China | 1 | 10% |
| France | 1 | 10% |
| Australia | 1 | 10% |
| Unknown | 3 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 60% |
| Scientists | 3 | 30% |
| Science communicators (journalists, bloggers, editors) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 230 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| Germany | 3 | 1% |
| Italy | 1 | <1% |
| Sweden | 1 | <1% |
| France | 1 | <1% |
| Denmark | 1 | <1% |
| Canada | 1 | <1% |
| Spain | 1 | <1% |
| China | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 215 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 72 | 31% |
| Researcher | 46 | 20% |
| Student > Master | 34 | 15% |
| Student > Bachelor | 14 | 6% |
| Student > Postgraduate | 11 | 5% |
| Other | 28 | 12% |
| Unknown | 25 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 75 | 33% |
| Biochemistry, Genetics and Molecular Biology | 61 | 27% |
| Computer Science | 37 | 16% |
| Medicine and Dentistry | 7 | 3% |
| Engineering | 5 | 2% |
| Other | 13 | 6% |
| Unknown | 32 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2017.
All research outputs
#5,446,994
of 25,374,647 outputs
Outputs from Genome Biology
#2,944
of 4,467 outputs
Outputs of similar age
#61,154
of 320,910 outputs
Outputs of similar age from Genome Biology
#92
of 123 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,910 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 123 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.