You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
| Title |
Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules
|
|---|---|
| Published in |
Biology Direct, August 2009
|
| DOI | 10.1186/1745-6150-4-31 |
| Pubmed ID | |
| Authors |
Ralf Dressel, Kaomei Guan, Jessica Nolte, Leslie Elsner, Sebastian Monecke, Karim Nayernia, Gerd Hasenfuss, Wolfgang Engel |
| Abstract |
Multipotent adult germ-line stem cells (maGSCs) represent a new pluripotent cell type that can be derived without genetic manipulation from spermatogonial stem cells (SSCs) present in adult testis. Similarly to induced pluripotent stem cells (iPSCs), they could provide a source of cellular grafts for new transplantation therapies of a broad variety of diseases. To test whether these stem cells can be rejected by the recipients, we have analyzed whether maGSCs and iPSCs can become targets for cytotoxic T lymphocytes (CTL) or whether they are protected, as previously proposed for embryonic stem cells (ESCs). |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Iran, Islamic Republic of | 1 | 2% |
| Germany | 1 | 2% |
| Australia | 1 | 2% |
| Unknown | 49 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 27% |
| Student > Ph. D. Student | 13 | 25% |
| Professor | 4 | 8% |
| Student > Postgraduate | 4 | 8% |
| Student > Master | 4 | 8% |
| Other | 7 | 13% |
| Unknown | 6 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 23 | 44% |
| Medicine and Dentistry | 8 | 15% |
| Biochemistry, Genetics and Molecular Biology | 5 | 10% |
| Veterinary Science and Veterinary Medicine | 1 | 2% |
| Environmental Science | 1 | 2% |
| Other | 6 | 12% |
| Unknown | 8 | 15% |