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The intracellular region of Notch ligands: does the tail make the difference?

Overview of attention for article published in Biology Direct, July 2007
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Title
The intracellular region of Notch ligands: does the tail make the difference?
Published in
Biology Direct, July 2007
DOI 10.1186/1745-6150-2-19
Pubmed ID
Authors

Alessandro Pintar, Alfredo De Biasio, Matija Popovic, Neli Ivanova

Abstract

The cytoplasmic tail of Notch ligands drives endocytosis, mediates association with proteins implicated in the organization of cell-cell junctions and, through regulated intra-membrane proteolysis, is released from the membrane as a signaling fragment. We survey these findings and discuss the role of Notch ligands intracellular region in bidirectional signaling and possibly in signal modulation in mammals.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Mexico 1 1%
United States 1 1%
Unknown 89 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 26%
Researcher 23 25%
Student > Master 12 13%
Student > Bachelor 6 7%
Student > Doctoral Student 6 7%
Other 9 10%
Unknown 12 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 38 41%
Biochemistry, Genetics and Molecular Biology 28 30%
Medicine and Dentistry 8 9%
Immunology and Microbiology 2 2%
Computer Science 1 1%
Other 0 0%
Unknown 15 16%