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Mendeley readers
| Title |
IgG3 deficiency extends lifespan and attenuates progression of glomerulonephritis in MRL/lprmice
|
|---|---|
| Published in |
Biology Direct, January 2012
|
| DOI | 10.1186/1745-6150-7-3 |
| Pubmed ID | |
| Authors |
Neil S Greenspan, Myro A Lu, Jacob W Shipley, Xuedong Ding, Qing Li, Dilara Sultana, Maria Kollaros, John R Schreiber, Pingfu Fu, Chaim Putterman, Steven N Emancipator |
| Abstract |
Antibodies of the IgG3 subclass have been implicated in the pathogenesis of the spontaneous glomerulonephritis observed in mice of the MRL/MpJ-Tnfrsf6lpr (MRL/lpr) inbred strain which have been widely studied as a model of systemic lupus erythematosus We have produced IgG3-deficient (-/-) mice with the MRL/lpr genetic background to determine whether IgG3 antibodies are necessary for or at least contributory to MRL/lpr-associated nephritis. |
Mendeley readers
The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 16 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 4 | 25% |
| Student > Ph. D. Student | 4 | 25% |
| Professor > Associate Professor | 2 | 13% |
| Librarian | 1 | 6% |
| Researcher | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 3 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 4 | 25% |
| Agricultural and Biological Sciences | 3 | 19% |
| Immunology and Microbiology | 2 | 13% |
| Biochemistry, Genetics and Molecular Biology | 1 | 6% |
| Unknown | 6 | 38% |