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CRISPR transcript processing: a mechanism for generating a large number of small interfering RNAs.

Overview of attention for article published in Biology Direct, July 2012
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Title
CRISPR transcript processing: a mechanism for generating a large number of small interfering RNAs.
Published in
Biology Direct, July 2012
DOI 10.1186/1745-6150-7-24
Pubmed ID
Abstract

CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated sequences) is a recently discovered prokaryotic defense system against foreign DNA, including viruses and plasmids. CRISPR cassette is transcribed as a continuous transcript (pre-crRNA), which is processed by Cas proteins into small RNA molecules (crRNAs) that are responsible for defense against invading viruses. Experiments in E. coli report that overexpression of cas genes generates a large number of crRNAs, from only few pre-crRNAs.

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
Germany 1 1%
Unknown 72 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 21 28%
Researcher 20 27%
Student > Master 7 9%
Professor > Associate Professor 5 7%
Student > Bachelor 5 7%
Other 11 15%
Unknown 5 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 42 57%
Biochemistry, Genetics and Molecular Biology 15 20%
Computer Science 4 5%
Physics and Astronomy 2 3%
Immunology and Microbiology 1 1%
Other 4 5%
Unknown 6 8%