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A new family of polymerases related to superfamily A DNA polymerases and T7-like DNA-dependent RNA polymerases

Overview of attention for article published in Biology Direct, October 2008
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1 patent

Citations

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32 Dimensions

Readers on

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41 Mendeley
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1 CiteULike
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1 Connotea
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Title
A new family of polymerases related to superfamily A DNA polymerases and T7-like DNA-dependent RNA polymerases
Published in
Biology Direct, October 2008
DOI 10.1186/1745-6150-3-39
Pubmed ID
Authors

Lakshminarayan M Iyer, Saraswathi Abhiman, L Aravind

Abstract

Using sequence profile methods and structural comparisons we characterize a previously unknown family of nucleic acid polymerases in a group of mobile elements from genomes of diverse bacteria, an algal plastid and certain DNA viruses, including the recently reported Sputnik virus. Using contextual information from domain architectures and gene-neighborhoods we present evidence that they are likely to possess both primase and DNA polymerase activity, comparable to the previously reported prim-pol proteins. These newly identified polymerases help in defining the minimal functional core of superfamily A DNA polymerases and related RNA polymerases. Thus, they provide a framework to understand the emergence of both DNA and RNA polymerization activity in this class of enzymes. They also provide evidence that enigmatic DNA viruses, such as Sputnik, might have emerged from mobile elements coding these polymerases.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Brazil 1 2%
Unknown 38 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 29%
Student > Ph. D. Student 11 27%
Student > Bachelor 4 10%
Student > Master 4 10%
Professor > Associate Professor 3 7%
Other 5 12%
Unknown 2 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 56%
Biochemistry, Genetics and Molecular Biology 12 29%
Environmental Science 1 2%
Psychology 1 2%
Chemistry 1 2%
Other 0 0%
Unknown 3 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2008.
All research outputs
#7,439,080
of 22,741,406 outputs
Outputs from Biology Direct
#263
of 487 outputs
Outputs of similar age
#31,857
of 89,418 outputs
Outputs of similar age from Biology Direct
#1
of 1 outputs
Altmetric has tracked 22,741,406 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 487 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 89,418 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them