↓ Skip to main content

Comparative genomic analysis of the DUF71/COG2102 family predicts roles in diphthamide biosynthesis and B12 salvage.

Overview of attention for article published in Biology Direct, September 2012
Altmetric Badge

Citations

dimensions_citation
18 Dimensions

Readers on

mendeley
28 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Comparative genomic analysis of the DUF71/COG2102 family predicts roles in diphthamide biosynthesis and B12 salvage.
Published in
Biology Direct, September 2012
DOI 10.1186/1745-6150-7-32
Pubmed ID
Authors

de Crecy-Lagard V, Forouhar F, Brochier-Armanet C, Tong L, Hunt JF

Abstract

The availability of over 3000 published genome sequences has enabled the use of comparative genomic approaches to drive the biological function discovery process. Classically, one used to link gene with function by genetic or biochemical approaches, a lengthy process that often took years. Phylogenetic distribution profiles, physical clustering, gene fusion, co-expression profiles, structural information and other genomic or post-genomic derived associations can be now used to make very strong functional hypotheses. Here, we illustrate this shift with the analysis of the DUF71/COG2102 family, a subgroup of the PP-loop ATPase family.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 2 7%
Unknown 26 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 29%
Researcher 7 25%
Professor > Associate Professor 3 11%
Student > Bachelor 2 7%
Student > Master 2 7%
Other 3 11%
Unknown 3 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 46%
Biochemistry, Genetics and Molecular Biology 6 21%
Unspecified 1 4%
Environmental Science 1 4%
Computer Science 1 4%
Other 2 7%
Unknown 4 14%