Title |
Association among H. pylori virulence markers dupA, cagA and vacA in Brazilian patients
|
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Published in |
Journal of Venomous Animals and Toxins including Tropical Diseases, January 2014
|
DOI | 10.1186/1678-9199-20-1 |
Pubmed ID | |
Authors |
Weendelly Nayara Pereira, Mariane Avante Ferraz, Luanna Munhoz Zabaglia, Roger William de Labio, Wilson Aparecido Orcini, João Paulo Bianchi Ximenez, Agostinho Caleman Neto, Spencer Luiz Marques Payão, Lucas Trevizani Rasmussen |
Abstract |
Only a few Helicobacter pylori-infected individuals develop severe gastric diseases and virulence factors of H. pylori appear to be involved in such clinical outcomes. Duodenal ulcer promoting gene A (dupA) is a novel virulence factor of Helicobacter pylori that is associated with duodenal ulcer development and reduced risk for gastric carcinoma in some populations. The aims of the present study were to determine the presence of dupA gene and evaluate the association among dupA and other virulence factors including cagA and vacA in Brazilian patients. Gastric biopsies were obtained from 205 dyspeptic patients (100 children and 105 adults). DNA was extracted and analyzed for the presence of H. pylori and its virulence factors using the polymerase chain reaction method. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 1 | 2% |
Unknown | 40 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 8 | 20% |
Student > Ph. D. Student | 7 | 17% |
Student > Doctoral Student | 5 | 12% |
Student > Postgraduate | 4 | 10% |
Researcher | 3 | 7% |
Other | 9 | 22% |
Unknown | 5 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 24% |
Biochemistry, Genetics and Molecular Biology | 8 | 20% |
Agricultural and Biological Sciences | 7 | 17% |
Immunology and Microbiology | 5 | 12% |
Unspecified | 2 | 5% |
Other | 4 | 10% |
Unknown | 5 | 12% |