Title |
Malignant Struma ovarii in a 30-year old nulliparous patient
|
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Published in |
Thyroid Research, May 2017
|
DOI | 10.1186/s13044-017-0038-1 |
Pubmed ID | |
Authors |
J. Colin Boyd, Blair A. Williams, Matthew H. Rigby, Katharina Kieser, Saul Offman, Hemlata Shirsat, Jonathan R. B. Trites, S. Mark Taylor, Robert D. Hart |
Abstract |
Struma ovarii is a rare monodermal germ cell tumor where the ovary is comprised of at least half thyroid tissue. This phenomenon may indicate an embryological origin. A 30-year old nulliparous woman presented with acute right lower quadrant pain and underwent laparoscopic right salpingo-oophorectomy. The excised ovarian mass showed evidence of struma-derived papillary thyroid carcinoma. Ultrasound of the thyroid showed mild enlargement with two solid nodules. A fine needle aspirate of a thyroid nodule was positive for malignancy and a total thyroidectomy was performed. Microscopic features of the thyroid were consistent with papillary thyroid carcinoma. The two tumours were considered as synchronous independent primaries based on their histological presentation. We believe that aggressive surgical management followed by radioiodine therapy is best to reduce recurrence risk and optimize survival. The broad scope of interventions needed to treat malignant struma ovarii require a strong interdisciplinary team. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 25% |
Researcher | 3 | 13% |
Student > Postgraduate | 2 | 8% |
Student > Master | 2 | 8% |
Other | 1 | 4% |
Other | 3 | 13% |
Unknown | 7 | 29% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 10 | 42% |
Biochemistry, Genetics and Molecular Biology | 2 | 8% |
Unspecified | 1 | 4% |
Immunology and Microbiology | 1 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Other | 2 | 8% |
Unknown | 7 | 29% |