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X Demographics
Mendeley readers
Attention Score in Context
| Title |
High mechanical strain of primary intervertebral disc cells promotes secretion of inflammatory factors associated with disc degeneration and pain
|
|---|---|
| Published in |
Arthritis Research & Therapy, January 2014
|
| DOI | 10.1186/ar4449 |
| Pubmed ID | |
| Authors |
Rahul Gawri, Derek H Rosenzweig, Emerson Krock, Jean A Ouellet, Laura S Stone, Thomas M Quinn, Lisbet Haglund |
| Abstract |
Excessive mechanical loading of intervertebral discs (IVD) is thought to alter matrix properties and influence disc cell metabolism, contributing to degenerative disc disease and development of discogenic pain. However, little is known about how mechanical strain induces these changes. This study investigated the cellular and molecular changes as well as which inflammatory receptors and cytokines were up-regulated in human intervertebral disc cells exposed to high mechanical strain (HMS) at low frequency. The impact of these metabolic changes on neuronal differentiation was also explored to determine a role in the development of disc degeneration and discogenic pain. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Canada | 1 | <1% |
| Unknown | 116 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 20% |
| Student > Master | 20 | 17% |
| Researcher | 15 | 13% |
| Student > Bachelor | 10 | 8% |
| Other | 7 | 6% |
| Other | 18 | 15% |
| Unknown | 25 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 22% |
| Agricultural and Biological Sciences | 21 | 18% |
| Engineering | 18 | 15% |
| Biochemistry, Genetics and Molecular Biology | 9 | 8% |
| Sports and Recreations | 4 | 3% |
| Other | 14 | 12% |
| Unknown | 27 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2014.
All research outputs
#16,720,137
of 25,371,288 outputs
Outputs from Arthritis Research & Therapy
#2,443
of 3,380 outputs
Outputs of similar age
#195,522
of 320,688 outputs
Outputs of similar age from Arthritis Research & Therapy
#34
of 60 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,380 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,688 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.