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Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny

Overview of attention for article published in Journal of Translational Medicine, January 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

twitter
2 X users
patent
1 patent
wikipedia
1 Wikipedia page

Citations

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15 Dimensions

Readers on

mendeley
40 Mendeley
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Title
Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny
Published in
Journal of Translational Medicine, January 2014
DOI 10.1186/1479-5876-12-27
Pubmed ID
Authors

Kiyonori Tanoue, Yuqing Wang, Minako Ikeda, Kaoru Mitsui, Rie Irie, Takao Setoguchi, Setsuro Komiya, Shoji Natsugoe, Ken-ichiro Kosai

Abstract

Effective methods for eradicating cancer stem cells (CSCs), which are highly tumorigenic and resistant to conventional therapies, are urgently needed. Our previous studies demonstrated that survivin-responsive conditionally replicating adenoviruses regulated with multiple factors (Surv.m-CRAs), which selectively replicate in and kill a broad range of cancer-cell types, are promising anticancer agents. Here we examined the therapeutic potentials of a Surv.m-CRA against rhabdomyosarcoma stem cells (RSCs), in order to assess its clinical effectiveness and usefulness.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Portugal 1 3%
Unknown 38 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 28%
Student > Bachelor 6 15%
Student > Ph. D. Student 5 13%
Student > Master 4 10%
Other 3 8%
Other 2 5%
Unknown 9 23%
Readers by discipline Count As %
Medicine and Dentistry 7 18%
Agricultural and Biological Sciences 6 15%
Biochemistry, Genetics and Molecular Biology 5 13%
Immunology and Microbiology 4 10%
Engineering 2 5%
Other 5 13%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 June 2023.
All research outputs
#4,750,854
of 23,923,788 outputs
Outputs from Journal of Translational Medicine
#770
of 4,232 outputs
Outputs of similar age
#55,922
of 313,899 outputs
Outputs of similar age from Journal of Translational Medicine
#25
of 117 outputs
Altmetric has tracked 23,923,788 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,232 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,899 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 117 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.