You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Serum thyroid-stimulating hormone and interleukin-8 levels in boys with autism spectrum disorder
|
|---|---|
| Published in |
Journal of Neuroinflammation, June 2017
|
| DOI | 10.1186/s12974-017-0888-4 |
| Pubmed ID | |
| Authors |
Sarika Singh, Umar Yazdani, Bharathi Gadad, Sayed Zaman, Linda S. Hynan, Nichole Roatch, Claire Schutte, C. Nathan Marti, Laura Hewitson, Dwight C. German |
| Abstract |
Autism spectrum disorder (ASD) affects approximately 1 in 68 children in the USA. An ASD blood biomarker may enable early diagnosis and/or identification of new therapeutic targets. Serum samples from ASD and typically developing (TD) boys (n = 30/group) were screened for differences in 110 proteins using a multiplex immunoassay. Eleven proteins were found that together could confirm ASD with modest accuracy using multiple training and test sets. Two of the 11 proteins identified here were further tested using a different detection platform and with a larger sample of ASD and TD boys. The two proteins, thyroid-stimulating hormone (TSH) and interleukin-8 (IL-8), have been previously identified as putative biomarkers for ASD. TSH levels were significantly lower in ASD boys, whereas IL-8 levels were significantly elevated. The diagnostic accuracy for ASD based upon TSH or IL-8 levels alone varied from 74 to 76%, but using both proteins together, the diagnostic accuracy increased to 82%. In addition, TSH levels were negatively correlated with the Autism Diagnostic Observation Schedule subdomain scores. These data suggest that a panel of proteins may be useful as a putative blood biomarker for ASD. |
X Demographics
The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 26% |
| United Kingdom | 3 | 13% |
| Spain | 1 | 4% |
| Saudi Arabia | 1 | 4% |
| Unknown | 12 | 52% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 16 | 70% |
| Practitioners (doctors, other healthcare professionals) | 3 | 13% |
| Scientists | 2 | 9% |
| Science communicators (journalists, bloggers, editors) | 2 | 9% |
Mendeley readers
The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 73 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 19% |
| Student > Ph. D. Student | 13 | 18% |
| Student > Bachelor | 9 | 12% |
| Researcher | 5 | 7% |
| Student > Doctoral Student | 3 | 4% |
| Other | 5 | 7% |
| Unknown | 24 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 13 | 18% |
| Medicine and Dentistry | 7 | 10% |
| Neuroscience | 6 | 8% |
| Social Sciences | 4 | 5% |
| Agricultural and Biological Sciences | 3 | 4% |
| Other | 14 | 19% |
| Unknown | 26 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 175. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2023.
All research outputs
#233,359
of 25,654,806 outputs
Outputs from Journal of Neuroinflammation
#17
of 2,969 outputs
Outputs of similar age
#4,893
of 332,426 outputs
Outputs of similar age from Journal of Neuroinflammation
#1
of 46 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,969 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,426 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.