↓ Skip to main content

Prevention strategies for Alzheimer’s disease

Overview of attention for article published in Translational Neurodegeneration, June 2012
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)

Mentioned by

facebook
10 Facebook pages
googleplus
2 Google+ users

Citations

dimensions_citation
22 Dimensions

Readers on

mendeley
52 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Prevention strategies for Alzheimer’s disease
Published in
Translational Neurodegeneration, June 2012
DOI 10.1186/2047-9158-1-13
Pubmed ID
Authors

Serge Gauthier, Liyong Wu, Pedro Rosa-Neto, Jianping Jia

Abstract

Symptomatic treatment during the dementia stage of Alzheimer's disease(AD) cannot delay or halt the progression of this disease. Therefore, prevention in the preclinical stage is likely the most effective way to decrease the incidence of this age-associated neurodegenerative condition, and its associated burden for individuals and society. Age, gender, family history, ApoE4, systolic blood pressure, body mass index, total cholesterol level and physical activity are all used as component of dementia risk score. There have been numerous challenges in conducting primary prevention trials in AD. Enrichment strategies for prevention studies include studying those subjects with more risk factors for AD, such as older age, those with a positive family history of late onset AD, and those who are ApoE4 positive. Each of these strategies is designed to increase the probability of developing AD thereby decreasing the sample size or the duration of follow up. Another strategy would be to target directly the pathophysiology of AD in its preclinical stages and use the biomarkers in prevention trial as surrogate markers. This will be done first in carriers of dominantly inherited early onset AD. As this research takes place networks of memory clinics must prepare to transfer new knowledge to persons interested in a preventive approach to AD.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Spain 1 2%
Netherlands 1 2%
Brazil 1 2%
Unknown 48 92%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 19%
Student > Master 8 15%
Student > Ph. D. Student 7 13%
Researcher 5 10%
Student > Doctoral Student 4 8%
Other 8 15%
Unknown 10 19%
Readers by discipline Count As %
Medicine and Dentistry 10 19%
Agricultural and Biological Sciences 7 13%
Psychology 7 13%
Neuroscience 4 8%
Nursing and Health Professions 4 8%
Other 5 10%
Unknown 15 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 March 2017.
All research outputs
#7,047,742
of 25,374,917 outputs
Outputs from Translational Neurodegeneration
#283
of 384 outputs
Outputs of similar age
#47,503
of 177,596 outputs
Outputs of similar age from Translational Neurodegeneration
#1
of 3 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.7. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 177,596 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them