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Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells

Overview of attention for article published in Breast Cancer Research, January 2014
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Citations

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69 Dimensions

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52 Mendeley
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Title
Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells
Published in
Breast Cancer Research, January 2014
DOI 10.1186/bcr3611
Pubmed ID
Authors

Manish Tandon, Zujian Chen, Jitesh Pratap

Abstract

The Runt-related transcription factor Runx2 is critical for skeletal development but is also aberrantly expressed in breast cancers, and promotes cell growth and invasion. A de-regulated serine/threonine kinase Akt signaling pathway is implicated in mammary carcinogenesis and cell survival; however the mechanisms underlying Runx2 role in survival of invasive breast cancer cells are still unclear.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 27%
Researcher 12 23%
Student > Bachelor 4 8%
Student > Doctoral Student 2 4%
Student > Master 2 4%
Other 6 12%
Unknown 12 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 33%
Biochemistry, Genetics and Molecular Biology 7 13%
Medicine and Dentistry 5 10%
Pharmacology, Toxicology and Pharmaceutical Science 4 8%
Engineering 2 4%
Other 4 8%
Unknown 13 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2014.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from Breast Cancer Research
#1,882
of 2,052 outputs
Outputs of similar age
#283,013
of 322,827 outputs
Outputs of similar age from Breast Cancer Research
#22
of 27 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,827 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.