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Literature evidence in open targets - a target validation platform

Overview of attention for article published in Journal of Biomedical Semantics, June 2017
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43 Mendeley
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Title
Literature evidence in open targets - a target validation platform
Published in
Journal of Biomedical Semantics, June 2017
DOI 10.1186/s13326-017-0131-3
Pubmed ID
Authors

Şenay Kafkas, Ian Dunham, Johanna McEntyre

Abstract

We present the Europe PMC literature component of Open Targets - a target validation platform that integrates various evidence to aid drug target identification and validation. The component identifies target-disease associations in documents and ranks the documents based on their confidence from the Europe PMC literature database, by using rules utilising expert-provided heuristic information. The confidence score of a given document represents how valuable the document is in the scope of target validation for a given target-disease association by taking into account the credibility of the association based on the properties of the text. The component serves the platform regularly with the up-to-date data since December, 2015. Currently, there are a total number of 1168365 distinct target-disease associations text mined from >26 million PubMed abstracts and >1.2 million Open Access full text articles. Our comparative analyses on the current available evidence data in the platform revealed that 850179 of these associations are exclusively identified by literature mining. This component helps the platform's users by providing the most relevant literature hits for a given target and disease. The text mining evidence along with the other types of evidence can be explored visually through https://www.targetvalidation.org and all the evidence data is available for download in json format from https://www.targetvalidation.org/downloads/data .

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Canada 1 2%
Unknown 41 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 30%
Other 5 12%
Student > Ph. D. Student 5 12%
Student > Doctoral Student 2 5%
Student > Bachelor 2 5%
Other 6 14%
Unknown 10 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 23%
Agricultural and Biological Sciences 6 14%
Computer Science 6 14%
Medicine and Dentistry 5 12%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 4 9%
Unknown 10 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2017.
All research outputs
#17,898,929
of 22,979,862 outputs
Outputs from Journal of Biomedical Semantics
#288
of 364 outputs
Outputs of similar age
#226,916
of 317,259 outputs
Outputs of similar age from Journal of Biomedical Semantics
#4
of 6 outputs
Altmetric has tracked 22,979,862 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 364 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,259 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.