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The impact of penicillin allergy labels on antibiotic and health care use in primary care: a retrospective cohort study

Overview of attention for article published in Clinical and Translational Allergy, June 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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Title
The impact of penicillin allergy labels on antibiotic and health care use in primary care: a retrospective cohort study
Published in
Clinical and Translational Allergy, June 2017
DOI 10.1186/s13601-017-0154-y
Pubmed ID
Authors

Tanly Su, Berna D. L. Broekhuizen, Theo J. M. Verheij, Heike Rockmann

Abstract

Suspected penicillin allergy (Pen-A) is often not verified by diagnostic testing. In third line penicillin allergy labels were associated with prescription of broad spectrum antibiotics, hospital stay duration and readmission. Assess the impact of Pen-A labels on antibiotic and health care use in primary care. A retrospective cohort study was conducted in primary care in the Utrecht area, the Netherlands. All patients registered with a penicillin allergy on 31 December 2013 were selected from the General Practitioner Network database. Each patient with a Pen-A label was matched for age, gender, follow-up period with three patients without Pen-A label. Risk (OR) of receiving a reserve and second choice antibiotic, number and type of antibiotics prescribed during follow-up and number of GP contacts were compared between the two cohorts. Of 196,440 patients, 1254 patients (0.6%) with a Pen-A label were identified and matched with 3756 patients without Pen-A label. Pen-A labels resulted in higher risk of receiving ≥1 antibiotic prescription per year (OR 2.56, 95% CI 2.05-3.20), ≥1 s choice antibiotic prescription per year (OR 2.21 95% CI 1.11-4.40), and ≥4 GP contacts per year (OR 1.71 95% CI 1.46-2.00). The chance of receiving tetracyclins (OR 2.24, 95% CI 1.29-3.89), macrolides/lincosamides/streptogamins (OR 8.69, 95% CI 4.26-17.73) and quinolones (OR 2.59, 95% CI 1.22-5.48) was higher in Pen-A patients. In primary health care Pen-A labels are associated with increased antibiotic use, including second choice antibiotics, and more health care use.

X Demographics

X Demographics

The data shown below were collected from the profiles of 34 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 13%
Other 5 10%
Researcher 5 10%
Student > Master 5 10%
Student > Bachelor 3 6%
Other 6 12%
Unknown 21 40%
Readers by discipline Count As %
Medicine and Dentistry 14 27%
Nursing and Health Professions 5 10%
Immunology and Microbiology 3 6%
Agricultural and Biological Sciences 2 4%
Social Sciences 2 4%
Other 6 12%
Unknown 20 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2017.
All research outputs
#1,800,497
of 23,577,654 outputs
Outputs from Clinical and Translational Allergy
#75
of 686 outputs
Outputs of similar age
#36,403
of 318,463 outputs
Outputs of similar age from Clinical and Translational Allergy
#3
of 10 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 686 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,463 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.