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Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts

Overview of attention for article published in Molecular Neurodegeneration, February 2013
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  • Average Attention Score compared to outputs of the same age

Mentioned by

peer_reviews
1 peer review site
facebook
1 Facebook page

Citations

dimensions_citation
7 Dimensions

Readers on

mendeley
39 Mendeley
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Title
Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts
Published in
Molecular Neurodegeneration, February 2013
DOI 10.1186/1750-1326-8-10
Pubmed ID
Authors

Badri Vardarajan, David Vergote, Fadel Tissir, Mark Logue, Jing Yang, Nathalie Daude, Kunie Ando, Ekaterina Rogaeva, Joseph Lee, Rong Cheng, Jean-Pierre Brion, Mahdi Ghani, Beipei Shi, Clinton T Baldwin, Satyabrata Kar, Richard Mayeux, Paul Fraser, André M Goffinet, Peter St George-Hyslop, Lindsay A Farrer, David Westaway

Abstract

P73 belongs to the p53 family of cell survival regulators with the corresponding locus Trp73 producing the N-terminally distinct isoforms, TAp73 and DeltaNp73. Recently, two studies have implicated the murine Trp73 in the modulation in phospho-tau accumulation in aged wild type mice and in young mice modeling Alzheimer's disease (AD) suggesting that Trp73, particularly the DeltaNp73 isoform, links the accumulation of amyloid peptides to the creation of neurofibrillary tangles (NFTs). Here, we reevaluated tau pathologies in the same TgCRND8 mouse model as the previous studies.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 21%
Professor 4 10%
Student > Bachelor 4 10%
Researcher 3 8%
Librarian 2 5%
Other 10 26%
Unknown 8 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 21%
Neuroscience 5 13%
Agricultural and Biological Sciences 4 10%
Medicine and Dentistry 3 8%
Chemistry 2 5%
Other 6 15%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2016.
All research outputs
#14,773,697
of 22,743,667 outputs
Outputs from Molecular Neurodegeneration
#697
of 845 outputs
Outputs of similar age
#190,884
of 307,820 outputs
Outputs of similar age from Molecular Neurodegeneration
#12
of 18 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 845 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,820 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.