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The stem cell factor antibody enhances the chemotherapeutic effect of adriamycin on chemoresistant breast cancer cells

Overview of attention for article published in Cancer Cell International, January 2012
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  • Average Attention Score compared to outputs of the same age
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

peer_reviews
1 peer review site

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
17 Mendeley
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Title
The stem cell factor antibody enhances the chemotherapeutic effect of adriamycin on chemoresistant breast cancer cells
Published in
Cancer Cell International, January 2012
DOI 10.1186/1475-2867-12-21
Pubmed ID
Authors

Neil D Jelly, Issam I Hussain, Jennifer Eremin, Oleg Eremin, Mohamed El-Sheemy

Abstract

The outcome of chemotherapy in breast cancer is strongly influenced by multidrug resistance (MDR). Several surrogate markers of chemoresistance have been identified including - CD24 (cluster differentiation 24) expression, stem cell growth factor (SCF), B-cell lymphocyte protein 2 (Bcl-2) and annexin V. The present study aimed to examine the expression of CD24 in the sensitive breast cancer cell line MCF-7 (Michigan Foudation-7) and MCF-7/adriamycin resistant (MCF-7/AdrRes) cells, and, if minimal effective doses of the anthracycline drug adriamycin (0.579 μM and 88.2 μM) would be enhanced by the antibody to SCF (anti-SCF).

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 29%
Other 3 18%
Student > Bachelor 3 18%
Student > Postgraduate 2 12%
Lecturer 1 6%
Other 3 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 41%
Medicine and Dentistry 5 29%
Physics and Astronomy 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Chemistry 1 6%
Other 0 0%
Unknown 2 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2014.
All research outputs
#7,884,445
of 12,566,211 outputs
Outputs from Cancer Cell International
#168
of 471 outputs
Outputs of similar age
#123,989
of 241,579 outputs
Outputs of similar age from Cancer Cell International
#15
of 31 outputs
Altmetric has tracked 12,566,211 research outputs across all sources so far. This one is in the 23rd percentile – i.e., 23% of other outputs scored the same or lower than it.
So far Altmetric has tracked 471 research outputs from this source. They receive a mean Attention Score of 2.9. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,579 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.