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The stem cell factor antibody enhances the chemotherapeutic effect of adriamycin on chemoresistant breast cancer cells

Overview of attention for article published in Cancer Cell International, May 2012
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Mentioned by

peer_reviews
1 peer review site

Citations

dimensions_citation
6 Dimensions

Readers on

mendeley
18 Mendeley
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Title
The stem cell factor antibody enhances the chemotherapeutic effect of adriamycin on chemoresistant breast cancer cells
Published in
Cancer Cell International, May 2012
DOI 10.1186/1475-2867-12-21
Pubmed ID
Authors

Neil D Jelly, Issam I Hussain, Jennifer Eremin, Oleg Eremin, Mohamed El-Sheemy

Abstract

The outcome of chemotherapy in breast cancer is strongly influenced by multidrug resistance (MDR). Several surrogate markers of chemoresistance have been identified including - CD24 (cluster differentiation 24) expression, stem cell growth factor (SCF), B-cell lymphocyte protein 2 (Bcl-2) and annexin V. The present study aimed to examine the expression of CD24 in the sensitive breast cancer cell line MCF-7 (Michigan Foudation-7) and MCF-7/adriamycin resistant (MCF-7/AdrRes) cells, and, if minimal effective doses of the anthracycline drug adriamycin (0.579 μM and 88.2 μM) would be enhanced by the antibody to SCF (anti-SCF).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 6%
Unknown 17 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 28%
Student > Bachelor 3 17%
Other 3 17%
Lecturer 2 11%
Student > Postgraduate 2 11%
Other 3 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 39%
Medicine and Dentistry 5 28%
Nursing and Health Professions 1 6%
Biochemistry, Genetics and Molecular Biology 1 6%
Physics and Astronomy 1 6%
Other 1 6%
Unknown 2 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 March 2014.
All research outputs
#17,283,763
of 25,371,288 outputs
Outputs from Cancer Cell International
#1,291
of 2,231 outputs
Outputs of similar age
#117,082
of 178,787 outputs
Outputs of similar age from Cancer Cell International
#3
of 4 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,231 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,787 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.