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Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells

Overview of attention for article published in Journal of Neuroinflammation, February 2014
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  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

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1 X user
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1 patent

Citations

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69 Dimensions

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61 Mendeley
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Title
Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells
Published in
Journal of Neuroinflammation, February 2014
DOI 10.1186/1742-2094-11-24
Pubmed ID
Authors

Gunjan Dhawan Manocha, Ritu Mishra, Nikhil Sharma, Kanhaiya Lal Kumawat, Anirban Basu, Sunit K Singh

Abstract

Japanese encephalitis virus (JEV) infection leads to Japanese encephalitis (JE) in humans. JEV is transmitted through mosquitoes and maintained in a zoonotic cycle. This cycle involves pigs as the major reservoir, water birds as carriers and mosquitoes as vectors. JEV invasion into the central nervous system (CNS) may occur via antipodal transport of virions or through the vascular endothelial cells. Microglial cells get activated in response to pathogenic insults. JEV infection induces the innate immune response and triggers the production of type I interferons. The signaling pathway of type I interferon production is regulated by a number of molecules. TRIM proteins are known to regulate the expression of interferons; however, the involvement of TRIM genes and their underlying mechanism during JEV infection are not known.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Unknown 60 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 25%
Student > Master 10 16%
Researcher 7 11%
Student > Bachelor 4 7%
Student > Doctoral Student 4 7%
Other 9 15%
Unknown 12 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 36%
Immunology and Microbiology 10 16%
Biochemistry, Genetics and Molecular Biology 7 11%
Veterinary Science and Veterinary Medicine 2 3%
Neuroscience 2 3%
Other 5 8%
Unknown 13 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 May 2023.
All research outputs
#7,386,762
of 23,862,416 outputs
Outputs from Journal of Neuroinflammation
#1,227
of 2,768 outputs
Outputs of similar age
#86,160
of 314,268 outputs
Outputs of similar age from Journal of Neuroinflammation
#22
of 60 outputs
Altmetric has tracked 23,862,416 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 2,768 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,268 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.