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Mendeley readers
Attention Score in Context
| Title |
Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors
|
|---|---|
| Published in |
Molecular Cancer, August 2006
|
| DOI | 10.1186/1476-4598-5-31 |
| Pubmed ID | |
| Authors |
Francesco Marampon, Carmela Ciccarelli, Bianca M Zani |
| Abstract |
Expression of c-myc proto-oncogene is inappropriate in a wide range of human tumors, and is a downstream target of Ras/Raf/ERK pathway, which promotes c-Myc stability by enhancing c-Myc expression and activity. The aim of this study was to investigate whether the oncogenic phenotype in the human muscle-derived Rhabdomyosarcoma (RD) cell line and in non muscle-derived human tumor cell lines (SW403, IGR39 and PC3) can be blocked by disrupting the c-Myc pathway either by means of pharmacological MEK/ERK inhibition or by direct inactivation of the c-Myc protein. |
Mendeley readers
The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 2% |
| United Kingdom | 1 | 1% |
| Japan | 1 | 1% |
| Unknown | 89 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 23% |
| Student > Bachelor | 14 | 15% |
| Researcher | 11 | 12% |
| Student > Master | 5 | 5% |
| Professor | 4 | 4% |
| Other | 16 | 17% |
| Unknown | 22 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 27 | 29% |
| Agricultural and Biological Sciences | 18 | 19% |
| Medicine and Dentistry | 12 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
| Chemical Engineering | 1 | 1% |
| Other | 4 | 4% |
| Unknown | 27 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 March 2015.
All research outputs
#15,293,290
of 22,743,667 outputs
Outputs from Molecular Cancer
#1,039
of 1,716 outputs
Outputs of similar age
#57,206
of 65,747 outputs
Outputs of similar age from Molecular Cancer
#3
of 3 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,716 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 65,747 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one.