Title |
Studies of inactivation mechanism of non-enveloped icosahedral virus by a visible ultrashort pulsed laser
|
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Published in |
Virology Journal, February 2014
|
DOI | 10.1186/1743-422x-11-20 |
Pubmed ID | |
Authors |
Shaw-Wei D Tsen, David H Kingsley, Christian Poweleit, Samuel Achilefu, Douglas S Soroka, TC Wu, Kong-Thon Tsen |
Abstract |
Low-power ultrashort pulsed (USP) lasers operating at wavelengths of 425 nm and near infrared region have been shown to effectively inactivate viruses such as human immunodeficiency virus (HIV), M13 bacteriophage, and murine cytomegalovirus (MCMV). It was shown previously that non-enveloped, helical viruses such as M13 bacteriophage, were inactivated by a USP laser through an impulsive stimulated Raman scattering (ISRS) process. Recently, enveloped virus like MCMV has been shown to be inactivated by a USP laser via protein aggregation induced by an ISRS process. However, the inactivation mechanism for a clinically important class of viruses--non-enveloped, icosahedral viruses remains unknown. |
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Geographical breakdown
Country | Count | As % |
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United States | 1 | 25% |
Spain | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
Unknown | 60 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 14 | 23% |
Student > Ph. D. Student | 8 | 13% |
Unspecified | 7 | 11% |
Student > Doctoral Student | 6 | 10% |
Student > Master | 6 | 10% |
Other | 14 | 23% |
Unknown | 6 | 10% |
Readers by discipline | Count | As % |
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Physics and Astronomy | 9 | 15% |
Agricultural and Biological Sciences | 9 | 15% |
Biochemistry, Genetics and Molecular Biology | 7 | 11% |
Unspecified | 7 | 11% |
Medicine and Dentistry | 3 | 5% |
Other | 14 | 23% |
Unknown | 12 | 20% |