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Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways

Overview of attention for article published in BMC Infectious Diseases, December 2013
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Title
Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways
Published in
BMC Infectious Diseases, December 2013
DOI 10.1186/1471-2334-13-587
Pubmed ID
Authors

Amanda Farage Frade, Cristina Wide Pissetti, Barbara Maria Ianni, Bruno Saba, Hui Tzu Lin-Wang, Luciana Gabriel Nogueira, Ariana de Melo Borges, Paula Buck, Fabrício Dias, Monique Baron, Ludmila Rodrigues Pinto Ferreira, Andre Schmidt, José Antonio Marin-Neto, Mario Hirata, Marcelo Sampaio, Abílio Fragata, Alexandre Costa Pereira, Eduardo Donadi, Jorge Kalil, Virmondes Rodrigues, Edecio Cunha-Neto, Christophe Chevillard

Abstract

Chagas disease, caused by the protozoan Trypanosoma cruzi is endemic in Latin America. Thirty percent of infected individuals develop chronic Chagas cardiomyopathy (CCC), an inflammatory dilated cardiomyopathy that is, by far, the most important clinical consequence of T. cruzi infection. The others remain asymptomatic (ASY). A possible genetic component to disease progression was suggested by familial aggregation of cases and the association of markers of innate and adaptive immunity genes with CCC development. Migration of Th1-type T cells play a major role in myocardial damage.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Brazil 1 1%
Unknown 68 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 19%
Researcher 12 17%
Professor 7 10%
Student > Bachelor 7 10%
Student > Ph. D. Student 5 7%
Other 14 20%
Unknown 12 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 21%
Immunology and Microbiology 13 19%
Medicine and Dentistry 12 17%
Biochemistry, Genetics and Molecular Biology 8 11%
Environmental Science 1 1%
Other 4 6%
Unknown 17 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2014.
All research outputs
#15,293,290
of 22,743,667 outputs
Outputs from BMC Infectious Diseases
#4,445
of 7,663 outputs
Outputs of similar age
#192,421
of 307,122 outputs
Outputs of similar age from BMC Infectious Diseases
#73
of 121 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,663 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,122 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 121 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.