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Early start and stop of biologics: has the time come?

Overview of attention for article published in BMC Medicine, February 2014
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2 X users

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Title
Early start and stop of biologics: has the time come?
Published in
BMC Medicine, February 2014
DOI 10.1186/1741-7015-12-25
Pubmed ID
Authors

Ronald F van Vollenhoven, György Nagy, Paul P Tak

Abstract

Despite considerable advances in the management of rheumatoid arthritis, results are still not satisfactory for all patients. The treatment goal in rheumatoid arthritis is remission, and there currently are numerous conventional and biological medications available to reach this aim. There are also different treatment strategies but with only limited comparative evidence about their efficacies. More patients now achieve remission while on treatment, but it remains elusive in the majority of patients. Treatment-free remission, the ultimate goal of therapy, is only achieved in very few patients; even when this happens, it is most likely due to the natural course of the disease rather than to any specific therapies. Modern treatment is based on the initiation of aggressive therapy as soon as the diagnosis is established, and on modifying or intensifying therapy guided by frequent assessment of disease activity. In this commentary we will discuss the current treatment paradigm as well as the possibility of an induction-maintenance regimen with biological disease-modifying antirheumatic drugs in early rheumatoid arthritis.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 3%
Germany 1 3%
Canada 1 3%
Unknown 29 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 28%
Other 8 25%
Researcher 4 13%
Student > Postgraduate 3 9%
Student > Bachelor 2 6%
Other 5 16%
Unknown 1 3%
Readers by discipline Count As %
Medicine and Dentistry 16 50%
Arts and Humanities 3 9%
Agricultural and Biological Sciences 2 6%
Chemistry 2 6%
Mathematics 1 3%
Other 5 16%
Unknown 3 9%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2014.
All research outputs
#17,712,213
of 22,743,667 outputs
Outputs from BMC Medicine
#3,114
of 3,413 outputs
Outputs of similar age
#220,776
of 307,252 outputs
Outputs of similar age from BMC Medicine
#56
of 60 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,413 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.5. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,252 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.