Title |
Oligofructose supplementation during pregnancy and lactation impairs offspring development and alters the intestinal properties of 21-d-old pups
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Published in |
Lipids in Health and Disease, February 2014
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DOI | 10.1186/1476-511x-13-26 |
Pubmed ID | |
Authors |
Laís Vales Mennitti, Lila Missae Oyama, Juliana Lopez de Oliveira, Ana Claudia Losinskas Hachul, Aline Boveto Santamarina, Aline Alves de Santana, Marcos Hiromu Okuda, Eliane Beraldi Ribeiro, Claudia Maria da Penha Oller do Nascimento, Luciana Pellegrini Pisani |
Abstract |
Previously, we showed that the intake of trans fatty acids during pregnancy and lactation triggers a pro-inflammatory status in the offspring. On the other hand, prebiotics can alter the intestinal environment, reducing serum lipopolysaccharides (LPS) concentrations. This study evaluated the effect of the oligofructose 10% diet supplementation in the presence or absence of hydrogenated vegetable fat during pregnancy and lactation on the development, endotoxemia and bacterial composition of 21-d-old offspring. |
X Demographics
Geographical breakdown
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France | 1 | 100% |
Demographic breakdown
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Mendeley readers
Geographical breakdown
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United States | 1 | 2% |
Unknown | 50 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Doctoral Student | 9 | 18% |
Student > Ph. D. Student | 8 | 16% |
Student > Master | 7 | 14% |
Other | 5 | 10% |
Student > Bachelor | 4 | 8% |
Other | 5 | 10% |
Unknown | 13 | 25% |
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Physics and Astronomy | 2 | 4% |
Other | 7 | 14% |
Unknown | 15 | 29% |