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Mendeley readers
Attention Score in Context
| Title |
Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury
|
|---|---|
| Published in |
Acta Neuropathologica Communications, February 2014
|
| DOI | 10.1186/2051-5960-2-16 |
| Pubmed ID | |
| Authors |
Jennifer D Sokolowski, Kanchana K Gamage, Daniel S Heffron, Andrea C LeBlanc, Christopher D Deppmann, James W Mandell |
| Abstract |
Axon degeneration is a characteristic feature of multiple neuropathologic states and is also a mechanism of physiological neurodevelopmental pruning. The vast majority of in vivo studies looking at axon degeneration have relied on the use of classical silver degeneration stains, which have many limitations including lack of molecular specificity and incompatibility with immunolabeling methods. Because Wallerian degeneration is well known to involve cytoskeletal disassembly and because caspases are recently implicated in aspects of this process, we asked whether antibodies directed at caspase-generated neoepitopes of beta-actin and alpha-tubulin would be useful immunohistochemical markers of pathological and developmental axon degeneration. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 83 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 24% |
| Researcher | 16 | 19% |
| Student > Master | 11 | 13% |
| Student > Bachelor | 7 | 8% |
| Professor > Associate Professor | 5 | 6% |
| Other | 9 | 11% |
| Unknown | 17 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 20 | 24% |
| Neuroscience | 17 | 20% |
| Biochemistry, Genetics and Molecular Biology | 15 | 18% |
| Medicine and Dentistry | 7 | 8% |
| Psychology | 2 | 2% |
| Other | 6 | 7% |
| Unknown | 18 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2014.
All research outputs
#18,363,356
of 22,743,667 outputs
Outputs from Acta Neuropathologica Communications
#1,228
of 1,369 outputs
Outputs of similar age
#229,337
of 307,209 outputs
Outputs of similar age from Acta Neuropathologica Communications
#24
of 37 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,369 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,209 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.