Title |
Computational developments in microRNA-regulated protein-protein interactions
|
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Published in |
BMC Systems Biology, February 2014
|
DOI | 10.1186/1752-0509-8-14 |
Pubmed ID | |
Authors |
Wei Zhu, Yi-Ping Phoebe Chen |
Abstract |
Protein-protein interaction (PPI) is one of the most important functional components of a living cell. Recently, researchers have been interested in investigating the correlation between PPI and microRNA, which has been found to be a regulator at the post-transcriptional level. Studies on miRNA-regulated PPI networks will not only facilitate an understanding of the fine tuning role that miRNAs play in PPI networks, but will also provide potential candidates for tumor diagnosis. This review describes basic studies on the miRNA-regulated PPI network in the way of bioinformatics which includes constructing a miRNA-target protein network, describing the features of miRNA-regulated PPI networks and overviewing previous findings based on analysing miRNA-regulated PPI network features. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 2% |
Turkey | 1 | 2% |
Unknown | 42 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 25% |
Student > Master | 8 | 18% |
Researcher | 5 | 11% |
Student > Bachelor | 3 | 7% |
Student > Doctoral Student | 2 | 5% |
Other | 9 | 20% |
Unknown | 6 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 39% |
Biochemistry, Genetics and Molecular Biology | 8 | 18% |
Computer Science | 5 | 11% |
Engineering | 4 | 9% |
Environmental Science | 1 | 2% |
Other | 3 | 7% |
Unknown | 6 | 14% |