Title |
Genetic variation at aryl hydrocarbon receptor (AHR) loci in populations of Atlantic killifish (Fundulus heteroclitus) inhabiting polluted and reference habitats
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Published in |
BMC Ecology and Evolution, January 2014
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DOI | 10.1186/1471-2148-14-6 |
Pubmed ID | |
Authors |
Adam M Reitzel, Sibel I Karchner, Diana G Franks, Brad R Evans, Diane Nacci, Denise Champlin, Verónica M Vieira, Mark E Hahn |
Abstract |
The non-migratory killifish Fundulus heteroclitus inhabits clean and polluted environments interspersed throughout its range along the Atlantic coast of North America. Several populations of this species have successfully adapted to environments contaminated with toxic aromatic hydrocarbon pollutants such as polychlorinated biphenyls (PCBs). Previous studies suggest that the mechanism of resistance to these and other "dioxin-like compounds" (DLCs) may involve reduced signaling through the aryl hydrocarbon receptor (AHR) pathway. Here we investigated gene diversity and evidence for positive selection at three AHR-related loci (AHR1, AHR2, AHRR) in F. heteroclitus by comparing alleles from seven locations ranging over 600 km along the northeastern US, including extremely polluted and reference estuaries, with a focus on New Bedford Harbor (MA, USA), a PCB Superfund site, and nearby reference sites. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 25% |
United States | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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New Zealand | 1 | 2% |
United States | 1 | 2% |
Unknown | 61 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 14 | 22% |
Student > Ph. D. Student | 14 | 22% |
Student > Master | 13 | 21% |
Student > Bachelor | 5 | 8% |
Other | 4 | 6% |
Other | 8 | 13% |
Unknown | 5 | 8% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 27 | 43% |
Environmental Science | 10 | 16% |
Biochemistry, Genetics and Molecular Biology | 9 | 14% |
Nursing and Health Professions | 2 | 3% |
Medicine and Dentistry | 2 | 3% |
Other | 3 | 5% |
Unknown | 10 | 16% |