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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer’s disease
|
|---|---|
| Published in |
Acta Neuropathologica Communications, February 2014
|
| DOI | 10.1186/2051-5960-2-17 |
| Pubmed ID | |
| Authors |
Sonia George, Annica Rönnbäck, Gunnar K Gouras, Géraldine H Petit, Fiona Grueninger, Bengt Winblad, Caroline Graff, Patrik Brundin |
| Abstract |
The progressive development of Alzheimer's disease (AD) pathology follows a spatiotemporal pattern in the human brain. In a transgenic (Tg) mouse model of AD expressing amyloid precursor protein (APP) with the arctic (E693G) mutation, pathology spreads along anatomically connected structures. Amyloid-β (Aβ) pathology first appears in the subiculum and is later detected in interconnected brain regions, including the retrosplenial cortex. We investigated whether the spatiotemporal pattern of Aβ pathology in the Tg APP arctic mice to interconnected brain structures can be interrupted by destroying neurons using a neurotoxin and thereby disconnecting the neural circuitry. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Unknown | 77 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 19 | 24% |
| Student > Ph. D. Student | 12 | 15% |
| Student > Master | 10 | 13% |
| Student > Bachelor | 8 | 10% |
| Professor | 7 | 9% |
| Other | 7 | 9% |
| Unknown | 15 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 22 | 28% |
| Agricultural and Biological Sciences | 16 | 21% |
| Medicine and Dentistry | 5 | 6% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Other | 9 | 12% |
| Unknown | 19 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2021.
All research outputs
#5,979,035
of 22,743,667 outputs
Outputs from Acta Neuropathologica Communications
#884
of 1,369 outputs
Outputs of similar age
#72,458
of 313,031 outputs
Outputs of similar age from Acta Neuropathologica Communications
#10
of 37 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,369 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.8. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,031 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.