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The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

Overview of attention for article published in Journal of Translational Medicine, June 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)

Mentioned by

twitter
5 tweeters
facebook
1 Facebook page

Citations

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12 Dimensions

Readers on

mendeley
61 Mendeley
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Title
The era of bioengineering: how will this affect the next generation of cancer immunotherapy?
Published in
Journal of Translational Medicine, June 2017
DOI 10.1186/s12967-017-1244-2
Pubmed ID
Authors

Michele Graciotti, Cristiana Berti, Harm-Anton Klok, Lana Kandalaft

Abstract

Immunotherapy consists of activating the patient's immune system to fight cancer and has the great potential of preventing future relapses thanks to immunological memory. A great variety of strategies have emerged to harness the immune system against tumors, from the administration of immunomodulatory agents that activate immune cells, to therapeutic vaccines or infusion of previously activated cancer-specific T cells. However, despite great recent progress many difficulties still remain, which prevent the widespread use of immunotherapy. Some of these limitations include: systemic toxicity, weak immune cellular responses or persistence over time and most ultimately costly and time-consuming procedures. Synthetic and natural biomaterials hold great potential to address these hurdles providing biocompatible systems capable of targeted local delivery, co-delivery, and controlled and/or sustained release. In this review we discuss some of the bioengineered solutions and approaches developed so far and how biomaterials can be further implemented to help and shape the future of cancer immunotherapy. The bioengineering strategies here presented constitute a powerful toolkit to develop safe and successful novel cancer immunotherapies.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 61 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 18%
Researcher 9 15%
Student > Doctoral Student 7 11%
Student > Master 7 11%
Student > Bachelor 5 8%
Other 11 18%
Unknown 11 18%
Readers by discipline Count As %
Engineering 9 15%
Immunology and Microbiology 8 13%
Biochemistry, Genetics and Molecular Biology 7 11%
Chemistry 6 10%
Medicine and Dentistry 5 8%
Other 17 28%
Unknown 9 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 November 2017.
All research outputs
#12,057,998
of 20,902,589 outputs
Outputs from Journal of Translational Medicine
#1,363
of 3,621 outputs
Outputs of similar age
#133,316
of 284,264 outputs
Outputs of similar age from Journal of Translational Medicine
#1
of 1 outputs
Altmetric has tracked 20,902,589 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,621 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.0. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,264 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them