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MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies

Overview of attention for article published in Acta Neuropathologica Communications, February 2014
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Title
MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies
Published in
Acta Neuropathologica Communications, February 2014
DOI 10.1186/2051-5960-2-22
Pubmed ID
Authors

Harald Lund, Elin Gustafsson, Anne Svensson, Maria Nilsson, Margareta Berg, Dan Sunnemark, Gabriel von Euler

Abstract

The progression of Alzheimer's disease (AD) is associated with an increase of phosphorylated tau in the brain. One of the earliest phosphorylated sites on tau is Ser262 that is preferentially phosphorylated by microtubule affinity regulating kinase (MARK), of which four isoforms exist. Herein we investigated the expression of MARK1-4 in the hippocampus of non-demented elderly (NDE) and AD cases.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 54 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 28%
Student > Bachelor 10 19%
Student > Doctoral Student 6 11%
Researcher 5 9%
Student > Master 5 9%
Other 7 13%
Unknown 6 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 19%
Medicine and Dentistry 8 15%
Agricultural and Biological Sciences 8 15%
Neuroscience 6 11%
Chemistry 4 7%
Other 8 15%
Unknown 10 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2014.
All research outputs
#3,062,776
of 4,507,509 outputs
Outputs from Acta Neuropathologica Communications
#130
of 186 outputs
Outputs of similar age
#75,235
of 111,423 outputs
Outputs of similar age from Acta Neuropathologica Communications
#19
of 26 outputs
Altmetric has tracked 4,507,509 research outputs across all sources so far. This one is in the 20th percentile – i.e., 20% of other outputs scored the same or lower than it.
So far Altmetric has tracked 186 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 111,423 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.